Acute kidney injury secondary to obstructive bladder malakoplakia: a case report

Abstract Background Malakoplakia is a rare granulomatous inflammatory condition that can affect immunosuppressed patients. The genitourinary system the most involved organ. We present case of kidney failure caused by obstructing bladder lesions, clinically suspicious for malignancy and pathologically proven to be malakoplakia. Case presentation A 70-year-old woman presented with acute injury Escherichia coli (E.coli) bacteremia. Investigation showed bilateral hydronephrosis thickening renal pelvises suggestive urothelial malignancy. Cystourethroscopy revealed multiple lesions completely obliterating both ureteral orifices. Pathology resected confirmed diagnosis Patient was treated prolonged antibiotic course over 6 months recovery her function. Conclusion mimic invasive tumors, only attained through histopathology which uniquely demonstrates pathognomonic Michaelis–Gutmann inclusions inside sheets histiocytes. Treatment largely dependent on antibiotics therapy must cover common isolated pathogen, E.coli.